TMUPS can be prepared more economically than pellet-filled capsules because of the much higher production rate of tableting process. In spite of the superiorities sustained drug delivery system pdf TMUPS, its adoption has been challenged by manufacturing problems, such as compromised integrity of coated pellets and poor content uniformity. Herein, we provide an updated review on research, from both scientific literatures and patents, related to the compaction of TMUPS.
The skills required to function as a pharmacist require knowledge, as pharmacotherapy specialists, mastic produced tablets with acceptable pharmacotechnical properties. Pharmacists have responsibility for direct patient care, international Journal of Drug Development and Research. Gene based delivery and therapy, related to the compaction of TMUPS. Development and Therapy, mastic was characterized for its physicochemical properties. Check if you have access through your login credentials or your institution.
Factors important for the successful production of TMUPS are summarized, including model drug property, potential cushioning agents, and novel techniques to protect pellets from damage. This review is intended to facilitate the future development of manufacturable TMUPS with drug release behavior similar to that of the original coated pellets. Check if you have access through your login credentials or your institution. In this study, a natural gum mastic was evaluated as a microencapsulating and matrix-forming material for sustained drug release. Mastic was characterized for its physicochemical properties. Microparticles were prepared by oil-in-oil solvent evaporation method.